Assay Detail
Binding
CHEMBL5350821
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Binding affinity to ACLY (unknown origin) assessed as inhibition constant
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Opportunities and Challenges for Inhibitors Targeting Citrate Transport and Metabolism in Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.76 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5418421 | — | — | 1 | 6.00 |
| CHEMBL120648 | — | — | 1 | 5.92 |
| CHEMBL118918 | — | — | 1 | 5.92 |
| CHEMBL116883 | — | — | 1 | 5.92 |
| CHEMBL121948 | — | — | 1 | 5.92 |
| CHEMBL414883 | RADICICOL | — | 1 | 4.89 |
| CHEMBL5406616 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5418421 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL120648 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL118918 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL116883 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL121948 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL414883 | RADICICOL | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL5406616 | — | Ki | = | 7000000.0 | nM | - |