Assay Detail
Toxicity
CHEMBL5351369
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MRC5 cells incubated for 72 hrs by WST-1 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | MRC5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of Bleomycin-Inspired RNA Ligands Targeting the Biogenesis of Oncogenic miRNAs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.78 | 4.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5428849 | — | — | 1 | 4.78 |
| CHEMBL5422790 | — | — | 1 | - |
| CHEMBL5413573 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5428849 | — | IC50 | = | 16600.0 | nM | 4.78 |
| CHEMBL5422790 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5413573 | — | IC50 | > | 100000.0 | nM | - |