Assay Detail
Functional
CHEMBL5351371
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Antiproliferative activity against human N13-1300 cells incubated for 72 hrs by WST-1 assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | N13-1300 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis of Bleomycin-Inspired RNA Ligands Targeting the Biogenesis of Oncogenic miRNAs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.53 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL810 | TEMOZOLOMIDE | 4.0 | 1 | 4.68 |
| CHEMBL5422790 | — | — | 1 | 4.66 |
| CHEMBL5413573 | — | — | 1 | 4.61 |
| CHEMBL5428849 | — | — | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL810 | TEMOZOLOMIDE | IC50 | = | 20800.0 | nM | 4.68 |
| CHEMBL5422790 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL5413573 | — | IC50 | = | 24500.0 | nM | 4.61 |
| CHEMBL5428849 | — | IC50 | = | 67300.0 | nM | 4.17 |