Assay Detail
Binding
CHEMBL5351478
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Binding affinity to dopamine D4 receptor (unknown origin) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Exploring Structural Determinants of Bias among D4 Subtype-Selective Dopamine Receptor Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.45 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3480577 | UCSF924 | — | 1 | 8.52 |
| CHEMBL5290993 | — | — | 1 | 8.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3480577 | UCSF924 | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL5290993 | — | Ki | = | 4.3 | nM | 8.37 |