Assay Detail
Binding
CHEMBL5352099
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Inhibition of HDAC6 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of Novel 1,2,3,4-Tetrahydrobenzofuro[2,3-<i>c</i>]pyridine Histone Deacetylase Inhibitors for Efficient Treatment of Hepatocellular Carcinoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.37 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2103863 | ABEXINOSTAT | 3.0 | 1 | 7.72 |
| CHEMBL5419989 | — | — | 1 | 7.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2103863 | ABEXINOSTAT | IC50 | = | 19.1 | nM | 7.72 |
| CHEMBL5419989 | — | IC50 | = | 97.2 | nM | 7.01 |