Assay Detail
Functional
CHEMBL5352545
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against human MV4-11 cells xenografted in BALB/c mouse at 0.6 mg/kg, po qd 21 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MV4-11 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.11 | 9.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5426612 | — | — | 1 | 9.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5426612 | — | IC50 | = | 0.77 | nM | 9.11 |