Assay Detail
Binding
CHEMBL5352776
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant MAO-B (unknown origin) incubated for 60 mins by luminescence based flow cytometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of novel indole derivatives as highly potent and efficacious LSD1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.14 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5399676 | — | — | 1 | 6.14 |
| CHEMBL4863608 | — | — | 1 | - |
| CHEMBL3989843 | TRANYLCYPROMINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5399676 | — | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL4863608 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL3989843 | TRANYLCYPROMINE | IC50 | > | 20000.0 | nM | - |