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Assay Detail

CHEMBL5352863

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against Plasmodium berghei ANKA infected in mouse assessed as reduction in parasitemia at 50 micromol/kg,po administrated for 4 days by Giemsa staining based microscopic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium berghei
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium berghei (CHEMBL612653)
Type ORGANISM
Organism Plasmodium berghei

Publication

New structural classes of antimalarials.
Rathod GK, Jain M, Sharma KK, Das S, Basak A, Jain R.
Eur J Med Chem (2022) 242 : 114653 -114653
PubMed 35985254 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3885085 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3885085 IC50 = 40.0 nM 7.40