Assay Detail
Functional
CHEMBL5352879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplasmodial activity against Plasmodium falciparum NF54 gametocytes infected in human erythrocyte assessed as inhibition of parasite growthVincubated for 48 hrs by SYBR Green dye based fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Cell Type | Erythrocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New structural classes of antimalarials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.71 | 7.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL119096 | CRYPTOLEPINE | — | 1 | 7.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL119096 | CRYPTOLEPINE | IC50 | = | 19.65 | nM | 7.71 |