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Assay Detail

CHEMBL5353392

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mouse GRK5
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

G protein-coupled receptor kinase 5 (CHEMBL3721302)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Targeting GRK2 and GRK5 for treating chronic degenerative diseases: Advances and future perspectives.
Zhang Y, Zhang J, Wang J, Chen H, Ouyang L, Wang Y.
Eur J Med Chem (2022) 243 : 114668 -114668
PubMed 36055000 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.05 5.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1096 AMLEXANOX 4.0 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1096 AMLEXANOX IC50 = 8860.0 nM 5.05