Assay Detail
Functional
CHEMBL5355306
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Inhibition of melanogenesis in human MNT-1 cells incubated for 96 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MNT-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Resorcinol-based hemiindigoid derivatives as human tyrosinase inhibitors and melanogenesis suppressors in human melanoma cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.52 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5408197 | — | — | 1 | 4.54 |
| CHEMBL5399906 | — | — | 1 | 4.50 |
| CHEMBL287556 | KOJIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5408197 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL5399906 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 15000000.0 | nM | - |