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Assay Detail

CHEMBL5355387

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MIA PaCa-2 cells incubated for 24 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MIA PaCa-2
Confidence 1 — Organism
Curated By Autocuration

Target

MIA PaCa-2 (CHEMBL614725)
Type CELL-LINE
Organism Homo sapiens

Publication

Resveratrol derivatives: Synthesis and their biological activities.
Grau L, Soucek R, Pujol MD.
Eur J Med Chem (2023) 246 : 114962 -114962
PubMed 36463729 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 4.31 4.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3220147 1 4.55
CHEMBL296411 TRISMETHOXYRESVERATROL 1 4.46
CHEMBL5430375 1 4.41
CHEMBL5436858 1 4.10
CHEMBL5419610 1 4.02
CHEMBL5414592 1 -
CHEMBL165 RESVERATROL 3.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3220147 IC50 = 28000.0 nM 4.55
CHEMBL296411 TRISMETHOXYRESVERATROL IC50 = 35000.0 nM 4.46
CHEMBL5430375 IC50 = 39000.0 nM 4.41
CHEMBL5436858 IC50 = 79000.0 nM 4.10
CHEMBL5419610 IC50 = 96000.0 nM 4.02
CHEMBL5414592 IC50 = 198000.0 nM -
CHEMBL165 RESVERATROL IC50 = 132000.0 nM -