Assay Detail
Functional
CHEMBL5355440
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2903 strain promastigotes assessed as reduction in cell viability incubated for 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania braziliensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.27 | 4.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL601739 | — | — | 1 | 4.36 |
| CHEMBL5396057 | — | — | 1 | 4.33 |
| CHEMBL3905744 | — | — | 1 | 4.32 |
| CHEMBL3914732 | — | — | 1 | 4.18 |
| CHEMBL5287746 | — | — | 1 | 4.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL601739 | — | IC50 | = | 44160.0 | nM | 4.36 |
| CHEMBL5396057 | — | IC50 | = | 46440.0 | nM | 4.33 |
| CHEMBL3905744 | — | IC50 | = | 48230.0 | nM | 4.32 |
| CHEMBL3914732 | — | IC50 | = | 65690.0 | nM | 4.18 |
| CHEMBL5287746 | — | IC50 | = | 70980.0 | nM | 4.15 |