Assay Detail
Functional
CHEMBL5355441
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania infantum MHOM/BR/74/PP75 strain promastigotes assessed as reduction in cell viability incubated for 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.43 | 4.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3914732 | — | — | 1 | 4.63 |
| CHEMBL5396057 | — | — | 1 | 4.52 |
| CHEMBL3905744 | — | — | 1 | 4.45 |
| CHEMBL601739 | — | — | 1 | 4.39 |
| CHEMBL5287746 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3914732 | — | IC50 | = | 23450.0 | nM | 4.63 |
| CHEMBL5396057 | — | IC50 | = | 30360.0 | nM | 4.52 |
| CHEMBL3905744 | — | IC50 | = | 35900.0 | nM | 4.45 |
| CHEMBL601739 | — | IC50 | = | 40890.0 | nM | 4.39 |
| CHEMBL5287746 | — | IC50 | = | 68770.0 | nM | 4.16 |