Assay Detail
Functional
CHEMBL5355446
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania panamensis MHOM/CO/87/UA140-EpiR-GFP strain amastigotes assessed as inhibition of parasite growth incubated for 72 hrs by flow cytometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania panamensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.00 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5177826 | — | — | 1 | 5.17 |
| CHEMBL5409781 | — | — | 1 | 4.96 |
| CHEMBL5434366 | — | — | 1 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5177826 | — | IC50 | = | 6720.0 | nM | 5.17 |
| CHEMBL5409781 | — | IC50 | = | 10920.0 | nM | 4.96 |
| CHEMBL5434366 | — | IC50 | = | 13930.0 | nM | 4.86 |