Assay Detail
Functional
CHEMBL5355451
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania amazonensis promastigotes assessed as inhibition of parasite growth
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania amazonensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.36 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5423282 | — | — | 1 | 6.70 |
| CHEMBL5437314 | — | — | 1 | 5.52 |
| CHEMBL443508 | PHENYLBUTYL ISOSELENOCYANATE | — | 1 | 5.35 |
| CHEMBL4439993 | — | — | 1 | 4.95 |
| CHEMBL5420787 | — | — | 1 | 4.28 |
| CHEMBL5397436 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5423282 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL5437314 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL443508 | PHENYLBUTYL ISOSELENOCYANATE | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL4439993 | — | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL5420787 | — | IC50 | = | 52900.0 | nM | 4.28 |
| CHEMBL5397436 | — | IC50 | > | 100000.0 | nM | - |