Assay Detail
Functional
CHEMBL5355454
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Antileishmanial activity against Leishmania donovani promastigotes assessed as inhibition of parasite growth measured after 24 hrs by Alamar blue based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.24 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5414462 | — | — | 1 | 6.80 |
| CHEMBL5409005 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5414462 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL5409005 | — | IC50 | = | 2070.0 | nM | 5.68 |