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Assay Detail

CHEMBL5355455

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antileishmanial activity against Leishmania aethiopica amastigotes assessed as inhibition of parasite growth measured after 24 hrs by Alamar blue based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania aethiopica
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania aethiopica (CHEMBL612651)
Type ORGANISM
Organism Leishmania aethiopica

Publication

Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases.
Henriquez-Figuereo A, Morán-Serradilla C, Angulo-Elizari E, Sanmartín C, Plano D.
Eur J Med Chem (2023) 246 : 115002 -115002
PubMed 36493616 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.81 5.97

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5409005 1 5.97
CHEMBL5414462 1 5.65

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5409005 IC50 = 1080.0 nM 5.97
CHEMBL5414462 IC50 = 2240.0 nM 5.65