Assay Detail
Binding
CHEMBL5356850
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human full-length recombinant HDAC1 incubated for 2 hrs by fluorescence based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Zinc-Binding Group Effect: Lessons from Non-Hydroxamic Acid Vorinostat Analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.38 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5407992 | — | — | 1 | 5.52 |
| CHEMBL2417783 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5407992 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL2417783 | — | IC50 | = | 5700.0 | nM | 5.24 |