Assay Detail
Binding
CHEMBL5357141
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Metallo-beta-lactamase VIM-2 assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Metallo-beta-lactamase VIM-2 (CHEMBL1255123) ↗| Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa |
Publication
Small-molecule inhibitors of bacterial-producing metallo-β-lactamases: insights into their resistance mechanisms and biochemical analyses of their activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.72 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5396807 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5396807 | — | Ki | = | 1900.0 | nM | 5.72 |