Assay Detail
Binding
CHEMBL5357362
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Arabidopsis thaliana DHDPS1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Arabidopsis thaliana |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic (CHEMBL5465361) ↗| Type | SINGLE PROTEIN |
| Organism | Arabidopsis thaliana |
Publication
Enhancing allosteric inhibition of dihydrodipicolinate synthase through the design and synthesis of novel dimeric compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.32 | 4.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5437863 | — | — | 1 | 4.45 |
| CHEMBL2263549 | — | — | 1 | 4.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5437863 | — | IC50 | = | 35600.0 | nM | 4.45 |
| CHEMBL2263549 | — | IC50 | = | 66200.0 | nM | 4.18 |