Assay Detail
Binding
CHEMBL5357375
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full length recombinant human CDK2 expressed in Insect cell in presence of ATP
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Insect cell |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Research progress of anticancer drugs targeting CDK12.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.49 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5414905 | — | — | 1 | 7.40 |
| CHEMBL4649135 | — | — | 1 | 6.49 |
| CHEMBL5188909 | — | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5414905 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL4649135 | — | IC50 | = | 321.0 | nM | 6.49 |
| CHEMBL5188909 | — | IC50 | = | 2680.0 | nM | 5.57 |