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Assay Detail

CHEMBL5357470

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against human A549 cells xenografted in mouse assessed as tumor growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Pharmacological overview of hederagenin and its derivatives.
Huang X, Shen QK, Guo HY, Li X, Quan ZS.
RSC Med Chem (2023) 14 : 1858 -1884
PubMed 37859723 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.24 5.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL479310 HEDERACOLCHISIDE A 1 5.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL479310 HEDERACOLCHISIDE A IC50 = 5800.0 nM 5.24