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Assay Detail

CHEMBL5357592

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mouse serum XO
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL5465298)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Past, present and future of xanthine oxidase inhibitors: design strategies, structural and pharmacological insights, patents and clinical trials.
Singh A, Singh K, Sharma A, Kaur K, Chadha R, Singh Bedi PM.
RSC Med Chem (2023) 14 : 2155 -2191
PubMed 37974965 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1467 ALLOPURINOL 4.0 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1467 ALLOPURINOL IC50 = 300.0 nM 6.52