Assay Detail
Binding
CHEMBL5357602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of XO (unknown origin) using xanthine as substrate measured after 1 to 5 mins by spectrophotometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Past, present and future of xanthine oxidase inhibitors: design strategies, structural and pharmacological insights, patents and clinical trials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.64 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1467 | ALLOPURINOL | 4.0 | 1 | 5.75 |
| CHEMBL1244 | 3,4-DIHYDROXY-5-NITROBENZALDEHYDE | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1467 | ALLOPURINOL | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL1244 | 3,4-DIHYDROXY-5-NITROBENZALDEHYDE | IC50 | = | 3000.0 | nM | 5.52 |