Assay Detail
Binding
CHEMBL5358402
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse MPS1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Macrophage-expressed gene 1 protein (CHEMBL5465262) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Development of MPS1 Inhibitors: Recent Advances and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.66 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3422104 | — | — | 1 | 8.05 |
| CHEMBL3410060 | — | — | 1 | 7.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3422104 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL3410060 | — | IC50 | = | 55.0 | nM | 7.26 |