Assay Detail
Functional
CHEMBL5358749
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Cytotoxicity against human HeLa cells assessed as reduction in cell viability
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Research status of indole-modified natural products.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.58 | 7.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3942909 | — | — | 1 | 7.25 |
| CHEMBL5426777 | — | — | 1 | 7.16 |
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 6.68 |
| CHEMBL5274508 | — | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3942909 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL5426777 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL5274508 | — | IC50 | = | 5890.0 | nM | 5.23 |