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Assay Detail

CHEMBL5358770

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HGC-27 cells measured after 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HGC-27
Confidence 1 — Organism
Curated By Autocuration

Target

HGC-27 (CHEMBL1075463)
Type CELL-LINE
Organism Homo sapiens

Publication

Diversely functionalized isoquinolines and their core-embedded heterocyclic frameworks: a privileged scaffold for medicinal chemistry.
Vijayakumar A, Manod M, Krishna RB, Mathew A, Mohan C.
RSC Med Chem (2023) 14 : 2509 -2534
PubMed 38107174 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.12 5.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5193940 1 5.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5193940 IC50 = 7600.0 nM 5.12