Assay Detail
Functional
CHEMBL5360013
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Antibacterial activity against Yersinia enterocolitica infected in mouse RAW264.7 cells assessed as reduction in intracellular bacterial growth incubated for 24 hrs in presence of gentamicin by CFU assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Yersinia enterocolitica |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of new dibenzodiazepine derivatives as antibacterials against intracellular bacteria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.03 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5408093 | — | — | 1 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5408093 | — | EC50 | = | 930.0 | nM | 6.03 |