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Assay Detail

CHEMBL5360084

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-phytoplankton activity against Skeletonema grethae assessed as reduction in chlorophyll a level measured after 72 hrs by fluorescence based analysis
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Skeletonema costatum
Confidence 1 — Organism
Curated By Autocuration

Target

Skeletonema costatum (CHEMBL613052)
Type ORGANISM
Organism Skeletonema costatum

Publication

Precursor-Directed Biosynthesis of Antialgal Fluorinated Bacillamide Derivatives in <i>Bacillus atrophaeus</i>.
Saalim M, Liu S, Bennett SD, Zaleta-Pinet DA, Poulin RX, Clark BR.
J Nat Prod (2024) 87 : 388 -395
PubMed 38319739 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 14 5.27 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL123292 CYCLOHEXIMIDE 2.0 1 6.30
CHEMBL2253356 1 4.88
CHEMBL124076 1 4.63
CHEMBL5429271 1 -
CHEMBL5411725 1 -
CHEMBL5407710 1 -
CHEMBL5406396 1 -
CHEMBL5431610 1 -
CHEMBL5399767 1 -
CHEMBL284521 1 -
CHEMBL5398889 1 -
CHEMBL33171 NB-ACETYLTRYPTAMINE 1 -
CHEMBL254805 BACILLAMIDE C 1 -
CHEMBL254595 BACILLAMIDE A 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL123292 CYCLOHEXIMIDE IC50 = 500.0 nM 6.30
CHEMBL2253356 IC50 = 13100.0 nM 4.88
CHEMBL124076 IC50 = 23200.0 nM 4.63
CHEMBL5429271 IC50 > 200000.0 nM -
CHEMBL5411725 IC50 > 200000.0 nM -
CHEMBL5407710 IC50 > 200000.0 nM -
CHEMBL5406396 IC50 > 200000.0 nM -
CHEMBL5431610 IC50 > 200000.0 nM -
CHEMBL5399767 IC50 > 200000.0 nM -
CHEMBL284521 IC50 > 200000.0 nM -
CHEMBL5398889 IC50 > 200000.0 nM -
CHEMBL33171 NB-ACETYLTRYPTAMINE IC50 > 200000.0 nM -
CHEMBL254805 BACILLAMIDE C IC50 > 200000.0 nM -
CHEMBL254595 BACILLAMIDE A IC50 > 200000.0 nM -