Assay Detail

CHEMBL5360346

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Functional

Antiproliferative activity against Renal 1983 cells (unknown origin) assessed as inhibition of cell proliferation

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Not specified
Cell Type	Renal 1983 cell
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Structural Modification of Noscapine via Photoredox/Nickel Dual Catalysis for the Discovery of S-Phase Arresting Agents.

Li D, Liu C, Guo T, Zhu J, Guo J, Luo T, Liu Y, Shen W, Jiang B, Wang W, Yin Q, Zhang Y.
ACS Med Chem Lett (2024) 15 : 230 -238
PubMed 38352836 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.41	4.41

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL364713	NOSCAPINE	2.0	1	4.41

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL364713	NOSCAPINE	IC50	=	39000.0	nM	4.41