Assay Detail
Functional
CHEMBL5360465
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Agonist activity at 5-HT2A receptor (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.48 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5406172 | — | — | 1 | 8.00 |
| CHEMBL5434434 | — | — | 1 | 7.75 |
| CHEMBL5405688 | — | — | 1 | 6.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5406172 | — | EC50 | = | 9.9 | nM | 8.00 |
| CHEMBL5434434 | — | EC50 | = | 17.8 | nM | 7.75 |
| CHEMBL5405688 | — | EC50 | = | 203.0 | nM | 6.69 |