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Assay Detail

CHEMBL5360767

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine arginase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel enzyme inhibitors modulating the nitric oxide pathway.
Doman AJ, Tommasi S, Perkins MV, McKinnon RA, Mangoni AA, Nair PC.
Bioorg Med Chem (2022) 72 : 116970 -116970
PubMed 36063653 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.52 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL260629 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL260629 Ki = 30000.0 nM 4.52