Assay Detail
Functional
CHEMBL5360826
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anti-proliferative activity against human NCI-H226 expressing NF2 mutant assessed as cell growth inhibition by CellTiter-Glo Luminescent Cell Viability Assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H226 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A chemical perspective on the modulation of TEAD transcriptional activities: Recent progress, challenges, and opportunities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.42 | 8.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5198469 | — | — | 1 | 8.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5198469 | — | IC50 | = | 3.8 | nM | 8.42 |