Assay Detail
Binding
CHEMBL5361381
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant CD73
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting ecto-5'-nucleotidase: A comprehensive review into small molecule inhibitors and expression modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.39 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4127683 | — | — | 1 | 7.82 |
| CHEMBL5425035 | — | — | 1 | 5.17 |
| CHEMBL1780024 | PHELLIBAUMIN A | — | 1 | 4.77 |
| CHEMBL5428963 | — | — | 1 | 4.72 |
| CHEMBL5411458 | — | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4127683 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL5425035 | — | IC50 | = | 6720.0 | nM | 5.17 |
| CHEMBL1780024 | PHELLIBAUMIN A | IC50 | = | 17120.0 | nM | 4.77 |
| CHEMBL5428963 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL5411458 | — | IC50 | = | 35070.0 | nM | 4.46 |