Assay Detail
Binding
CHEMBL5361385
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human recombinant CD73 assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting ecto-5'-nucleotidase: A comprehensive review into small molecule inhibitors and expression modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.08 | 9.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4452072 | — | — | 1 | 9.50 |
| CHEMBL4755577 | — | — | 1 | 8.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4452072 | — | Ki | = | 0.318 | nM | 9.50 |
| CHEMBL4755577 | — | Ki | = | 2.21 | nM | 8.66 |