Assay Detail
Binding
CHEMBL5361402
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant Ecto-5'-nucleotidase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting ecto-5'-nucleotidase: A comprehensive review into small molecule inhibitors and expression modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.69 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5411508 | — | — | 1 | 6.54 |
| CHEMBL149463 | 3-ACETYLCOUMARIN | — | 1 | 5.33 |
| CHEMBL5436167 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5411508 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL149463 | 3-ACETYLCOUMARIN | IC50 | = | 4660.0 | nM | 5.33 |
| CHEMBL5436167 | — | IC50 | = | 6200.0 | nM | 5.21 |