Assay Detail
Binding
CHEMBL5361452
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Inhibition of Saccharomyces cerevisiae alpha-glucosidase type I using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by absorbance based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthetic α-glucosidase inhibitors as promising anti-diabetic agents: Recent developments and future challenges.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.57 | 4.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4458405 | — | — | 1 | 4.71 |
| CHEMBL404271 | ACARBOSE | 4.0 | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4458405 | — | IC50 | = | 19270.0 | nM | 4.71 |
| CHEMBL404271 | ACARBOSE | IC50 | = | 38250.0 | nM | 4.42 |