Assay Detail
Binding
CHEMBL5362940
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Mixed type inhibition of electric eel AChE using acetylthiocholine iodide as substrate assessed as inhibition constant of second plot of intercept preincubated for 5 mins followed by substrate addition and measured after 5 mins by Ellman's method based double reciprocal Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and anti-Alzheimer potential of novel α-amino phosphonate derivatives and probing their molecular interaction mechanism with acetylcholinesterase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.54 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5433354 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5433354 | — | Ki | = | 292.0 | nM | 6.54 |