Assay Detail
Functional
CHEMBL5363011
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MV4-11 cells assessed inhibition of cell growth incubated for 72 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MV4-11 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of pyrazolo[3,4-b]pyridine derivatives as novel and potent Mps1 inhibitors for the treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.08 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5410634 | — | — | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5410634 | — | IC50 | = | 823.0 | nM | 6.08 |