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Assay Detail

CHEMBL5363452

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to calf thymus DNA assessed as dissociation constant measured at 348 nm absorbance by UV-Vis spectroscopic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Target

Calf thymus DNA (CHEMBL612514)
Type NUCLEIC-ACID
Organism Bos taurus

Publication

Sequence-Specific Dual DNA Binding Modes and Cytotoxicities of N-6-Functionalized Norcryptotackieine Alkaloids.
Majhi B, Ganguly S, Palit S, Parwez A, Saha R, Basu G, Dutta S.
J Nat Prod (2023) 86 : 1667 -1676
PubMed 37285507 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 4.17 4.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5429614 1 4.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5429614 Kd = 67000.0 nM 4.17