Assay Detail
Functional
CHEMBL5363516
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Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability by CCK-8 assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phyllospongianes A-E, Dinorscalarane Sesterterpenes from the Marine Sponge <i>Phyllospongia foliascens</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.74 | 4.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5399306 | — | — | 1 | 4.88 |
| CHEMBL810 | TEMOZOLOMIDE | 4.0 | 1 | 4.84 |
| CHEMBL5411947 | — | — | 1 | 4.49 |
| CHEMBL5437546 | — | — | 1 | - |
| CHEMBL5434354 | — | — | 1 | - |
| CHEMBL5414208 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5399306 | — | IC50 | = | 13200.0 | nM | 4.88 |
| CHEMBL810 | TEMOZOLOMIDE | IC50 | = | 14400.0 | nM | 4.84 |
| CHEMBL5411947 | — | IC50 | = | 32300.0 | nM | 4.49 |
| CHEMBL5437546 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL5434354 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL5414208 | — | IC50 | > | 50000.0 | nM | - |