Assay Detail
Functional
CHEMBL5363520
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Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by CCK-8 assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phyllospongianes A-E, Dinorscalarane Sesterterpenes from the Marine Sponge <i>Phyllospongia foliascens</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.14 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5399306 | — | — | 1 | 5.70 |
| CHEMBL5411947 | — | — | 1 | 5.14 |
| CHEMBL5437546 | — | — | 1 | 4.99 |
| CHEMBL5434354 | — | — | 1 | 4.96 |
| CHEMBL5414208 | — | — | 1 | 4.89 |
| CHEMBL810 | TEMOZOLOMIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5399306 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL5411947 | — | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL5437546 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL5434354 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL5414208 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL810 | TEMOZOLOMIDE | IC50 | - | — | - |