Assay Detail
ADMET
CHEMBL5363752
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human CYP2C8 by fluorescence microplate reader assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.14 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5402764 | — | — | 1 | 5.25 |
| CHEMBL5400376 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5402764 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL5400376 | — | IC50 | = | 9600.0 | nM | 5.02 |