Assay Detail
Binding
CHEMBL5366019
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Binding affinity to CXCL2 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 9.00 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL216981 | NAVARIXIN ANHYDROUS | 2.0 | 1 | 10.30 |
| CHEMBL38182 | — | — | 1 | 8.50 |
| CHEMBL3039531 | DANIRIXIN | 2.0 | 1 | 8.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL216981 | NAVARIXIN ANHYDROUS | Kd | = | 0.05012 | nM | 10.30 |
| CHEMBL38182 | — | Kd | = | 3.162 | nM | 8.50 |
| CHEMBL3039531 | DANIRIXIN | Kd | = | 6.31 | nM | 8.20 |