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Assay Detail

CHEMBL5367200

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of His-tagged Escherichia coli ANS1 FabG using acetoacetyl-CoA as substrate by spectrometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Isolation and biological activity of natural chalcones based on antibacterial mechanism classification.
Wang S, Li C, Zhang L, Sun B, Cui Y, Sang F.
Bioorg Med Chem (2023) 93 : 117454 -117454
PubMed 37659218 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.85 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL128000 BUTEIN 1 5.00
CHEMBL129795 ISOLIQUIRITIGENIN 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL128000 BUTEIN IC50 = 10000.0 nM 5.00
CHEMBL129795 ISOLIQUIRITIGENIN IC50 = 20000.0 nM 4.70