Assay Detail
Functional
CHEMBL5367557
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human YUL-0019 cells harboring EGFR N771delinsFH mutant incubated for 72 hrs by Cell Titer-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | YUL-0019 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structural Mechanism and Inhibitors Targeting EGFR Exon 20 Insertion (Ex20ins) Mutations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.52 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3545154 | POZIOTINIB | 3.0 | 1 | 9.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3545154 | POZIOTINIB | IC50 | = | 0.3 | nM | 9.52 |