Assay Detail
Functional
CHEMBL5369306
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human NMC 11060 cell assessed as inhibition of cell growth incubated for 72 hrs by cell-titer glo assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NMC 11060 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and Characterization of 1,3-Dihydro-2<i>H</i>-benzo[<i>d</i>]azepin-2-ones as Rule-of-5 Compliant Bivalent BET Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.65 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5426022 | — | — | 1 | 9.10 |
| CHEMBL2017291 | — | — | 1 | 6.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5426022 | — | IC50 | = | 0.7943 | nM | 9.10 |
| CHEMBL2017291 | — | IC50 | = | 630.96 | nM | 6.20 |