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Assay Detail

CHEMBL5370123

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Functional
Antioxidant activity assessed as DPPH radical scavenging activity incubated for 60 min by DPPH assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Selenoneine-inspired selenohydantoins with glutathione peroxidase-like activity.
Alhasan R, Martins GM, de Castro PP, Saleem RSZ, Zaiter A, Fries-Raeth I, Kleinclauss A, Perrin-Sarrado C, Chaimbault P, da Silva Júnior EN, Gaucher C, Jacob C.
Bioorg Med Chem (2023) 94 : 117479 -117479
PubMed 37769443 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 11 4.38 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL196 ASCORBIC ACID 4.0 1 4.75
CHEMBL5415577 1 4.46
CHEMBL5396064 1 4.43
CHEMBL5431395 1 4.42
CHEMBL5425042 1 4.41
CHEMBL5397619 1 4.36
CHEMBL5432775 1 4.36
CHEMBL1543 GLUTATHIONE 3.0 1 4.30
CHEMBL5413073 1 4.22
CHEMBL5438366 1 4.05
CHEMBL51085 EBSELEN 3.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL196 ASCORBIC ACID EC50 = 17800.0 nM 4.75
CHEMBL5415577 EC50 = 35000.0 nM 4.46
CHEMBL5396064 EC50 = 37000.0 nM 4.43
CHEMBL5431395 EC50 = 38000.0 nM 4.42
CHEMBL5425042 EC50 = 39000.0 nM 4.41
CHEMBL5397619 EC50 = 44000.0 nM 4.36
CHEMBL5432775 EC50 = 44000.0 nM 4.36
CHEMBL1543 GLUTATHIONE EC50 = 50000.0 nM 4.30
CHEMBL5413073 EC50 = 60000.0 nM 4.22
CHEMBL5438366 EC50 = 89000.0 nM 4.05
CHEMBL51085 EBSELEN EC50 - -