Assay Detail

CHEMBL5370945

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of Dengue virus 3 nucleoside-2'O-methyltransferase

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	dengue virus type 3
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Perspectives on the current antiviral developments towards RNA-dependent RNA polymerase (RdRp) and methyltransferase (MTase) domains of dengue virus non-structural protein 5 (DENV-NS5).

Sreekanth GP.
Eur J Med Chem (2023) 256 : 115416 -115416
PubMed 37159959 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.00	4.00

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL398463	RTP	-1.0	1	4.00

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL398463	RTP	IC50	=	100000.0	nM	4.00